Home > Organosilicon Compounds> [2-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-6-hydroxy-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone

[2-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-6-hydroxy-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone

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Origin: China

Cas No: 174264-46-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

Property

CAS No.: 174264-46-1 Formula: C34H41NO4SSi Molecular Weight: 587.84400

Description

Protected Raloxifene.

Basic Info

Chemical Name	[2-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-6-hydroxy-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone
Synonyms	4'-tert-Butyldimethylsilyl-6-hydroxy Raloxifene; 6-Hydroxy-4 inverted exclamation mark-tert-butyldimethylsylyl Raloxifene;
CAS No.	174264-46-1
Molecular Formula	C34H41NO4SSi
Molecular Weight	587.84400
PSA	87.24000
LogP	8.69150

Properties

Density	1.15g/cm3
Boiling Point	706.195ºC at 760 mmHg
Flash Point	380.893ºC
Refractive Index	1.593
Vapor Pressure	0mmHg at 25°C

Synthesis Route

raloxifene+tert-butyldimethylsilyl chloride→[6-[tert-butyl(dimethyl)silyl]oxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone+[2-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-6-hydroxy-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone

Precursor

tert-butyldimethylsilyl chloride
raloxifene

Downstream Product

methyl (2S,3S,4S,5R,6S)-3,4,5-triacetyloxy-6-[[2-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-3-[4-(2-piperidin-1-ylethoxy)benzoyl]-1-benzothiophen-6-yl]oxy]oxane-2-carboxylate

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