Home > Organophosphorus Compounds> [2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl] dihydrogen phosphate

[2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl] dihydrogen phosphate

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Origin: China

Cas No: 222030-63-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 222030-63-9 Formula: C18H19Na2O8P Molecular Weight: 440.29200

Basic Info

Chemical Name	[2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl] dihydrogen phosphate
Synonyms	Combretastatin A-4 phosphate; CA 4DP; combretastatin A-4 dihydrogen phosphate; combretastatin A-4 phosphoric acid; UNII-I5590ES2QZ; Fosbretabulin;
CAS No.	222030-63-9
Molecular Formula	C18H19Na2O8P
Molecular Weight	440.29200
PSA	119.15000
LogP	4.23930

Properties

Density	1.342g/cm3
Boiling Point	611.8ºC at 760mmHg
Flash Point	323.8ºC
Refractive Index	1.609
Vapor Pressure	7.99E-16mmHg at 25°C

Synthesis Route

2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethenyl]phenol→[2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl] dihydrogen phosphate
[3,4-ditert-butyl-2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl] phosphate→[2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl] dihydrogen phosphate
3'-O-bis(trimethylsilylethoxy)phosphorylcombretastatin→[2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl] dihydrogen phosphate

Precursor

2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethenyl]phenol
[3,4-ditert-butyl-2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl] phosphate
3'-O-bis(trimethylsilylethoxy)phosphorylcombretastatin

Downstream Product

2-amino-2-(hydroxymethyl)propane-1,3-diol,[2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl] dihydrogen phosphate

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