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2-Methoxypyridine

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Origin: China

Cas No: 1628-89-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
1628-89-3
Other Names:
Pyridine, methoxy-
MF:
C6H7NO
EINECS No.:
1628-89-3
Place of Origin:
Anhui, China
Type:
Syntheses Material Intermediates
Purity:
99%
Brand Name:
GSK
Model Number:
1628-89-3
Application:
Chemical
Appearance:
White Endocardial pocket
CAS:
1628-89-3
MW:
109.13g/mol
Assay:
99%
Grade:
Phamaceutical Grade
Shelf life:
Aluminum foil bag
Storage:
Room Temperature
Packing:
1kg/Alu bag or 25kg/Drum
Brand:
GSK
Origin:
China
Packaging&Delivery
Packaging Details
1kg/Alu bag or 25kg/Drum
Packing method :Woven bag or draft paper bag atteched polyethylene endometrium bag packing tightly or as buyer request
Port
Any Port
Lead Time:
Quantity(Kilograms) 1 - 25 >25
Est. Time(days) 30 To be negotiated

Property

CAS No.: 1628-89-3 Formula: C6H7NO Molecular Weight: 109.12600

Description

2-Methoxypyridine can be used as an intermediate to synthesize 2-methoxy-3-pyridinesulfonyl chloride which is patented as a reactant used to prepare erythromycin macrolide antibiotics as antibacterial and antiprotozoal agents. It can also be used to prepare bicyclic iminopyrimidinones as Beta Amyloid Cleaving Enzyme-1 (BACE1) inhibitors.

Basic Info

Chemical Name	2-Methoxypyridine
Synonyms	2-methoxy-5-trifluoromethylpyridine; Pyridine, 2-methoxy-; methoxypyridine; 6-methoxypyridine; 1-methoxypyridine; 2-methoxy-pyridine; Pyridine,2-methoxy; 2-methoxyaniline;
CAS No.	1628-89-3
Molecular Formula	C6H7NO
Molecular Weight	109.12600
PSA	22.12000
LogP	1.09020

Properties

Appearance & Physical State	Colorless liquid
Density	1.038
Boiling Point	142ºC
Flash Point	32ºC
Refractive Index	1.501-1.503
Water Solubility	INSOLUBLE
Stability	Stable under normal temperatures and pressures.
Storage Condition	Flammables area
Vapor Pressure	7.11mmHg at 25°C

Safety Info

Hazard Class	3
Safety Statements	S26-S36
HS Code	2933399090
Packing Group	III
WGK Germany	3
RIDADR	UN 1993
Risk Statements	R10; R36/37/38
Hazard Codes	Xi
Caution Statement	P261; P305 + P351 + P338
Signal Word	Warning
Hazard Declaration	H226; H315; H319; H335
Symbol	GHS02, GHS07

Synthesis Route

chlorotrimethylsilane+2-Bromo-6-methoxypyridine→2-Methoxypyridine+(2-methoxypyridin-3-yl)-trimethylsilane
1-FLUOROPYRIDINIUM TRIFLATE→2-Methoxypyridine+2-PYRIDYL TRIFLUOROMETHANESULFONATE
1-FLUOROPYRIDINIUM TRIFLATE→2-Chloropyridine+2-Methoxypyridine

Precursor

Triethoxysilane
5-Bromo-2-methoxypyridine
2-methoxy-1-oxidopyridin-1-ium
chlorotrimethylsilane

Downstream Product

2-Methoxypyridine-4-boronic acid, pinacol ester
(2-OXOPYRIDIN-1(2H)-YL)ACETIC ACID
2-(3,4-dichlorophenyl)-6-methylsulfinyl-3,4-dihydro-2H-pyrano[2,3-b]pyridine
2-Phenyl-2-(pyridin-2-yl)acetonitrile

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