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2-oxobutanoic acid

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Origin: China

Cas No: 600-18-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
600-18-0
Other Names:
2-Oxobutyric acid
MF:
C4H6O3
EINECS No.:
209-986-9
Place of Origin:
Wuhan,China(Mainland)
Type:
anti-hair loss
Grade Standard:
Medicine Grade, Tech Grade
Usage:
Animal Pharmaceuticals
Brand Name:
hengheda
Model Number:
hhd- 2-Oxobutyric acid
Purity:
99%min
Product name:
Factory Supply Eplerenone
Appearance:
White powder
Function:
Pharmaceutical Raw Materials
Grade:
Tech grade,pharm grade
COA:
Available
Stock:
Available
Assay test method:
HPLC UV
Shelf Life:
2 Years
Packaging&Delivery
Packaging Details
5 grams/Al-foil bag
10 grams/Al-foil bag
100 grams/Al-foil bag
1kg/Al-foil bag
or upon customers' request.
Port
Main port in China
Lead Time:
Quantity(Grams) 1 - 1 >1
Est. Time(days) 7 To be negotiated

Property

CAS No.: 600-18-0 Formula: C4H6O3 Molecular Weight: 102.08900

Description

α-Ketobutyric acid is a product of the lysis of cystathionine. It is also one of the degradation products of threonine, produced by the catabolism of the amino acid by threonine dehydratase. It is also produced by the degradation of homocysteine and the metabolism of methionine.
α-Ketobutyric acid is transported into the mitochondrial matrix, where it is converted to propionyl-CoA by Branched-chain alpha-keto acid dehydrogenase complex. Further mitochondrial reactions produce succinyl CoA. This is first through the enzyme mitochondria Propionyl-CoA carboxylase with biotin as a cofactor to produce S-methylmalonyl-CoA. This is subsequently converted to R-methylmalonyl-CoA by mitochondrial methylmalonyl-CoA epimerase. Finally, mitochondrial methylmalonyl-CoA mutase with cofactor adenosylcobalamin produces succinyl-CoA which enters the citric acid cycle.

Basic Info

Chemical Name	2-oxobutanoic acid
Synonyms	Butanoic acid, 2-oxo-; 2-Oxobutyric acid;
CAS No.	600-18-0
Molecular Formula	C4H6O3
Molecular Weight	102.08900
PSA	54.37000
LogP	0.05010

Properties

Appearance & Physical State	colorless paste
Density	1.182 g/cm3
Boiling Point	84ºC (20 mmHg)
Melting Point	30-34ºC
Flash Point	81ºC
Storage Condition	-20ºC

Safety Info

Hazard Class	8
Safety Statements	S26-S36/37/39
HS Code	2918300090
Packing Group	III
WGK Germany	3
RIDADR	UN 1759
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

Water+proline→2-oxobutanoic acid+2-oxoglutaric acid
(-)-9-methylchorismic acid→2-oxobutanoic acid+α-keto-β-phenylbutyric acid
3-bromo-4-methoxy-N-[2-(4-methylphenyl)-1,3-benzoxazol-5-yl]benzamide→formic acid+2-oxobutanoic acid

Precursor

D-α-aminobutyric acid
2-oxoglutaric acid
(2R)-2-Hydroxybutanoic acid
1-aminocyclopropanecarboxylic acid

Downstream Product

Methyl 2-Oxobutanoate
L-α-aminobutyric acid
atrolactic acid
propiophenone

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