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Home > All categories> Food and Feed Additives> Feed Additives> Amino acids and small peptides> (2S,4R)-Methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride
Picture of (2S,4R)-Methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride

(2S,4R)-Methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride

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Origin: China

Cas No: 40216-83-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 40216-83-9 Formula: C6H12ClNO3 Molecular Weight: 181.61700

    Description

    trans-4-Hydroxy-L-proline derivative. A natural constituent of animal structural proteins such as collagen and elastin.

    Basic Info

    Chemical Name (2S,4R)-Methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride
    Synonyms

    trans-4-Hydroxy-L-proline Methyl Ester Hydrochloride;
    L-4-Hydroxyproline methyl ester hydrochloride;
    Methyl (2S,4R)-4-hydroxypyrrolidine-2-carboxylate;
    Methyl (2S,4R)-4-Hydroxypyrrolidine-2-carboxylate Hydrochloride;
    H-Hyp-OMe·HCl;
    Trans-4-Hydroxy-L-Proline Methyl Ester,Hydrochloride Salt;
    (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic Acid Methyl Ester Hydrochloride;

    CAS No. 40216-83-9
    Molecular Formula C6H12ClNO3
    Molecular Weight 181.61700
    PSA 58.56000
    LogP 0.01300

    Properties

    Boiling Point 247.2ºC at 760 mmHg
    Flash Point 103.3ºC
    Storage Condition 2-8ºC

    Safety Info

    HS Code 2933990090
    WGK Germany 3
    Hazard Codes Xi

    Synthesis Route

    Methanol+4-hydroxy-L-proline→(2S,4R)-Methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride
    4-hydroxy-L-proline+acetyl chloride→(2S,4R)-Methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride
    Methanol+Boc-L-Hydroxyproline→(2S,4R)-Methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride

    Precursor

    4-hydroxy-L-proline
    acetyl chloride
    Boc-L-Hydroxyproline
    H-Hyp-OH*HCl

    Downstream Product

    1-O-tert-butyl 2-O-methyl (2S,4S)-4-cyanopyrrolidine-1,2-dicarboxylate
    (2S,4R)-4-methyl-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
    Boc-trans-4-cyano-L-proline methyl ester
    (2S,4S)-1-Boc-2-cyano-4-fluoropyrrolidine

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