(2S,5R)-5-PHENYLPYRROLIDINE-2-CARBOXYLIC ACID

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Origin: China

Cas No: 158567-93-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 158567-93-2 Formula: C11H13NO2 Molecular Weight: 191.22600

Basic Info

Chemical Name	(2S,5R)-5-PHENYLPYRROLIDINE-2-CARBOXYLIC ACID
Synonyms	ethyl rac-trans-4-methyl-2-piperidinecarboxylate;
CAS No.	158567-93-2
Molecular Formula	C11H13NO2
Molecular Weight	191.22600
PSA	49.33000
LogP	1.89310

Properties

Density	1.186 g/cm3
Boiling Point	365.7ºC at 760 mmHg
Refractive Index	1.562
Vapor Pressure	5.43E-06mmHg at 25°C

Synthesis Route

(S)-5-Ethoxycarbonyl-2-phenyl-Δ1-pyrroline→(2S,5R)-5-PHENYLPYRROLIDINE-2-CARBOXYLIC ACID
Ethyl Boc-D-Pyroglutamate→(2S,5R)-5-PHENYLPYRROLIDINE-2-CARBOXYLIC ACID
phenylmagnesium bromide→(2S,5R)-5-PHENYLPYRROLIDINE-2-CARBOXYLIC ACID

Precursor

(S)-5-Ethoxycarbonyl-2-phenyl-Δ1-pyrroline
Ethyl Boc-D-Pyroglutamate
1-O-tert-butyl 2-O-ethyl (2S)-5-hydroxypyrrolidine-1,2-dicarboxylate
phenylmagnesium bromide

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