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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Active Pharmaceutical Ingredients (APIs)> Respiratory system> (3S,4R)-1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenylpiperidine-4-carboxylic acid
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(3S,4R)-1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenylpiperidine-4-carboxylic acid

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Origin: China

Cas No: 79516-68-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 79516-68-0 Formula: C26H29FN2O2 Molecular Weight: 420.51900

    Description

    Levocabastine (trade name Livostin) is a selective second-generation H1 receptor antagonists which was discovered at Janssen Pharmaceutica in 1979. It is used for allergic conjunctivitis.
    As well as acting as an antihistamine, levocabastine has also subsequently been found to act as a potent and selective antagonist for the neurotensin receptor NTS2, and was the first drug used to characterise the different neurotensin subtypes. This has made it a useful tool for the study of this receptor.
    The pharmaceutical drug Bilina is a combination of Levocabastine, benzalkonium chloride, and other components and is typically used in a 0.5mg/ml suspension as eye-drops, dispensed in 4ml bottles for the treatment of allergic conjunctivitis or similar allergic ocular conditions.

    Basic Info

    Chemical Name (3S,4R)-1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenylpiperidine-4-carboxylic acid
    Synonyms

    Levocabastin;
    Levocabastinum [Latin];
    Levocabastinum;
    Levocabastina;
    Livostin;
    levocabastine;
    Levocabastina [Spanish];
    Livostin (TN);
    levocobastine;
    Levocabastine [INN:BAN];
    UNII-H68BP06S81;

    CAS No. 79516-68-0
    Molecular Formula C26H29FN2O2
    Molecular Weight 420.51900
    PSA 64.33000
    LogP 4.83198

    Properties

    Density 1.23 g/cm3
    Boiling Point 589.9ºC at 760 mmHg
    Flash Point 310.5ºC
    Refractive Index 1.606

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