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Picture of 4-(4-Chloro-1-oxobutyl)-α,α-dimethylbenzeneacetic Acid Methyl Ester

4-(4-Chloro-1-oxobutyl)-α,α-dimethylbenzeneacetic Acid Methyl Ester

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Origin: China

Cas No: 154477-54-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Quick Details

    CAS No.:
    154477-54-0
    MF:
    C15H19ClO3
    Purity:
    98%
    Appearance:
    Liquid
    CAS:
    154477-54-0
    Product Name:
    methyl 2-(4-(4-chlorobutanoyl)phenyl)-2-methylpropanoate
    Assay:
    98%

    Packaging&Delivery

    Selling Units:
    Single item
    Single package size: 
    20X20X30 cm
    Single gross weight:
    1.100 kg
    Lead Time:
    Quantity(Kilograms)1 - 1000>1000
    Est. Time(days)5To be negotiated
  • Property

    CAS No.: 154477-54-0 Formula: C15H19ClO3 Molecular Weight: 282.76300

    Description

    Fexofenadine intermediate. Antihistaminic and antiallergic agent.

    Basic Info

    Chemical Name 4-(4-Chloro-1-oxobutyl)-α,α-dimethylbenzeneacetic Acid Methyl Ester
    Synonyms

    Methyl 2-(4-(4-chlorobutanoyl)phenyl)-2-methylpropanoate;
    methyl 2-[4-(4-chlorobutanoyl)phenyl]-2-methylpropanoate;

    CAS No. 154477-54-0
    Molecular Formula C15H19ClO3
    Molecular Weight 282.76300
    PSA 43.37000
    LogP 3.33890

    Properties

    Appearance & Physical State Light brown oily mass
    Density 1.121
    Boiling Point 396.513ºC at 760 mmHg
    Flash Point 149.639ºC
    Refractive Index 1.508
    Vapor Pressure 0mmHg at 25°C

    Safety Info

    HS Code 2918300090

    Synthesis Route

    2-[4-(4-Chlorobutanoyl)phenyl]-2-methylpropanoic acid4-(4-Chloro-1-oxobutyl)-α,α-dimethylbenzeneacetic Acid Methyl Ester
    2-[4-(4-Chlorobutanoyl)phenyl]-2-methylpropanoic acid+dimethyl sulfate4-(4-Chloro-1-oxobutyl)-α,α-dimethylbenzeneacetic Acid Methyl Ester
    (1-methoxy-2-methylprop-1-enoxy)-trimethylsilane+4-Bromo-4-Chlorobutyrophenone4-(4-Chloro-1-oxobutyl)-α,α-dimethylbenzeneacetic Acid Methyl Ester

    Precursor

    4-Bromo-4-Chlorobutyrophenone
    dimethyl sulfate
    2-[4-(4-Chlorobutanoyl)phenyl]-2-methylpropanoic acid
    (1-methoxy-2-methylprop-1-enoxy)-trimethylsilane

    Downstream Product

    methyl 2-[4-[4-(4-benzhydryloxypiperidin-1-yl)butanoyl]phenyl]-2-methylpropanoate
    methyl 2-[4-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butyl]phenyl]-2-methylpropanoate
    fexofenadine
    methyl 2-[4-[4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butanoyl]phenyl]-2-methylpropanoate,hydrochloride

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