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DIETHYLSTILBESTROL DIPROPIONATE

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Origin: China

Cas No: 130-80-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 130-80-3 Formula: C24H28O4 Molecular Weight: 380.47700

Description

Diethylstilbestrol dipropionate (brand names Agostilben, Biokeral, Clinestrol, Cyclen, Estilbin, Estril, Neobenzoestrol, Orestol, Oroestrol, Ostregenin, Prostilbene, Stilbestriol DP, Stilboestrolum Dipropionicum, Stilboestrol, Synestrin, Willestrol, others), or diethylstilbestrol dipropanoate, also known as stilboestrol dipropionate (BANM), is a synthetic, non-steroidal estrogen that was formerly marketed widely throughout Europe. It is an ester of diethylstilbestrol with propionic acid. The drug is one of the most potent estrogens known.

Basic Info

Chemical Name	DIETHYLSTILBESTROL DIPROPIONATE
Synonyms	Dibestil; Desd; Estroben; Phenol, 4,4‘-(1,2-diethyl-1,2-ethenediyl)bis-, dipropanoate, (E)-; cyrenb; Estilbin; Gynolett; Horfemine; Euvestin; Orestol;
CAS No.	130-80-3
Molecular Formula	C24H28O4
Molecular Weight	380.47700
PSA	52.60000
LogP	6.04820

Properties

Density	1.075g/cm3
Boiling Point	486.4ºC at 760mmHg
Flash Point	237ºC
Refractive Index	1.542
Vapor Pressure	1.29E-09mmHg at 25°C

Safety Info

Hazard Class	6.1(b)
HS Code	2917399090
Packing Group	III
RIDADR	UN 3249
Risk Statements	R45; R46; R61; R20/21/22
Hazard Codes	T

Synthesis Route

3.4-bis-(4-propionyloxy-phenyl)-hexadiene-(2t.4t)→DIETHYLSTILBESTROL DIPROPIONATE
Diethylstilbestrol+Propionic anhydride→DIETHYLSTILBESTROL DIPROPIONATE
E,E-Dienestrol→DIETHYLSTILBESTROL DIPROPIONATE

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Subcutaneous	TDLo - Lowest published toxic dose	Rodent - rat	80 mg/kg	1.Tumorigenic-equivocal tumorigenic agent by RTECS criteria 2.Endocrine-tumors 3.Endocrine-changes in growth hormone
Implant	TDLo - Lowest published toxic dose	Rodent - rat	113 mg/kg	1.Tumorigenic-equivocal tumorigenic agent by RTECS criteria 2.Endocrine-tumors
Implant	TDLo - Lowest published toxic dose	Rodent - guinea pig	5 mg/kg	1.Tumorigenic-equivocal tumorigenic agent by RTECS criteria 2.Reproductive-Tumorigenic effects-other reproductive system tumors