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Home > Organic Nitrogen Compounds> Methyl (2R,4S)-4-aminopyrrolidine-2-carboxylate, N1-BOC protected
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Methyl (2R,4S)-4-aminopyrrolidine-2-carboxylate, N1-BOC protected

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Origin: China

Cas No: 254881-77-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 254881-77-1 Formula: C11H20N2O4 Molecular Weight: 244.28700

    Basic Info

    Chemical Name Methyl (2R,4S)-4-aminopyrrolidine-2-carboxylate, N1-BOC protected
    Synonyms

    N-a-butoxycarbonyl-trans-4-amino-L-prolinemethyl ester;
    trans-4-amino-N-tert-butoxycarbonyl-D-proline methyl ester;
    (2R,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate;

    CAS No. 254881-77-1
    Molecular Formula C11H20N2O4
    Molecular Weight 244.28700
    PSA 81.86000
    LogP 1.13430

    Properties

    Density 1.151
    Boiling Point 321ºC
    Flash Point 148ºC
    Refractive Index 1.507

    Synthesis Route

    1N-tert-butoxycarbonyl-2(R)-carbomethoxy-4(S)-azidopyrrolidine→Methyl (2R,4S)-4-aminopyrrolidine-2-carboxylate, N1-BOC protected
    tert-butoxycarbonyl anhydride→Methyl (2R,4S)-4-aminopyrrolidine-2-carboxylate, N1-BOC protected
    Methyl (2R,4R)-1-Boc-4-hydroxypyrrolidine-2-carboxylate→Methyl (2R,4S)-4-aminopyrrolidine-2-carboxylate, N1-BOC protected

    Precursor

    Methyl (2R,4R)-1-Boc-4-hydroxypyrrolidine-2-carboxylate
    1N-tert-butoxycarbonyl-2(R)-carbomethoxy-4(R)-methanesulfonylpyrrolidine
    1N-tert-butoxycarbonyl-2(R)-carbomethoxy-4(S)-azidopyrrolidine
    tert-butoxycarbonyl anhydride

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