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N-Boc-4-piperidinemethanol

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Origin: China

Cas No: 123855-51-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Quick Details

    CAS No.:
    123855-51-6
    MF:
    C11H21NO3
    Place of Origin:
    China
    Type:
    Pharmaceutical Intermediates
    Purity:
    99.0%min
    Brand Name:
    HAOYAO
    Model Number:
    HY112711
    Application:
    Pharmaceutical Intermediates
    Appearance:
    White Powder

    Packaging&Delivery

    Packaging Details
    BAGS
    Port
    SHANGHAI TIANJIN YANTAI DALIAN
    Lead Time:
    Quantity(Kilograms)1 - 1000>1000
    Est. Time(days)7To be negotiated

    Products Description

    item
    value
    CAS No.
    123855-51-6
    MF
    C11H21NO3
    Place of Origin
    China
    Type
    Pharmaceutical Intermediates
    Purity
    99.0%min
    Brand Name
    HAOYAO
    Model Number
    HY112711
    Application
    Pharmaceutical Intermediates
    Appearance
    White Powder

  • Property

    CAS No.: 123855-51-6 Formula: C11H21NO3 Molecular Weight: 215.28900

    Description

    N-Boc-4-piperidinmethanol, is a Piperidine class derivative, used as an intermediate in the medical field. It is used in the synthesis of anticancer drug Vandetanib.

    Basic Info

    Chemical Name N-Boc-4-piperidinemethanol
    Synonyms

    1-(tert-Butoxycarbonyl)-4-piperidinemethanol;
    N-BOC-4-Piperidinemethanol;
    N-tert-Butyloxycarbonyl-4-piperidinemethanol;
    1-Boc-4-(hydroxymethyl)piperidine;
    tert-Butyl 4-(hydroxymethyl)piperidine-1-carboxylate;
    1-(tert-Butoxycarbonyl)-4-(hydroxymethyl)piperidine;
    1-Boc-4-piperidinemethanol;
    N-(tert-Butoxycarbonyl)-4-piperidinemethanol;

    CAS No. 123855-51-6
    Molecular Formula C11H21NO3
    Molecular Weight 215.28900
    PSA 49.77000
    LogP 1.56370

    Properties

    Density 1.059 g/cm3
    Boiling Point 308ºC at 760 mmHg
    Melting Point 78-82ºC
    Flash Point 140.1ºC
    Refractive Index 1.479
    Vapor Pressure 6.41E-05mmHg at 25°C

    Safety Info

    HS Code 2933399090
    WGK Germany 3
    Hazard Codes Xi

    Synthesis Route

    Ethyl N-Boc-piperidine-4-carboxylate→N-Boc-4-piperidinemethanol
    1-Boc-Piperidine-4-carboxylic Acid→N-Boc-4-piperidinemethanol
    4-Piperidinemethanol+tert-butoxycarbonyl anhydride→N-Boc-4-piperidinemethanol

    Precursor

    1-Boc-Piperidine-4-carboxylic Acid

    tert-butoxycarbonyl anhydride
    4-Piperidinemethanol

    Downstream Product

    tert-butyl 4-[(3-bromophenoxy)methyl]piperidine-1-carboxylate
    piperidine-4-carbaldehyde
    tert-Butyl 4-(chloromethyl)piperidine-1-carboxylate
    tert-butyl 4-(methylsulfonylmethyl)piperidine-1-carboxylate

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