Home > Organofluorine Compounds> TRIFLUOROMETHANESULFONAMIDE

TRIFLUOROMETHANESULFONAMIDE

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Origin: China

Cas No: 421-85-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 421-85-2 Formula: CH2F3NO2S Molecular Weight: 149.09200

Description

Trifluoromethylsulfonamide is a useful synthetic intermediate. It is used to prepare specific inhibitors of mammalian secreted phospholipases A2. It is also used to synthesize ecicosanoids with effects on renal vasoconstriction.

Basic Info

Chemical Name	TRIFLUOROMETHANESULFONAMIDE
Synonyms	1bcd; trifluoromethanesulphonamide; Trifluoromethylsulfonamide; trifluoro-methanesulfonic acid amide; TrifluoroMethanesulfonaMide; TRIFLUOROMETHANE SULFONAMIDE; Methanesulfonamide,1,1,1-trifluoro; triflylamine; trifluoromethyl-sulphonamide; Triflamide; 1,1,1-trifluoromethanesulfonamide; Methanesulfonamide, 1,1,1-trifluoro-;
CAS No.	421-85-2
Molecular Formula	CH2F3NO2S
Molecular Weight	149.09200
PSA	68.54000
LogP	1.57580

Properties

Density	1.73g/cm3
Boiling Point	164.6ºC at 760 mmHg
Melting Point	120-124ºC(lit.)
Flash Point	53.3ºC
Refractive Index	1.369
Vapor Pressure	1.95mmHg at 25°C

Safety Info

Safety Statements	S26-S36
HS Code	2935009090
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xn

Synthesis Route

Ammonia→Ammonium trifluoromethanesulfonate+TRIFLUOROMETHANESULFONAMIDE
N-trifluoromethylsulfonyl-(4-fluorophenyl)-carboximidoyl chloride+diazomethyl(trimethyl)silane→TRIFLUOROMETHANESULFONAMIDE+2-Chloro-4'-fluoroacetophenone
triflic anhydride+Ammonia→Ammonium trifluoromethanesulfonate+TRIFLUOROMETHANESULFONAMIDE

Downstream Product

chloromethyl-methoxy-dimethylsilane
2,2,6,6-tetramethyl-4-(trifluoromethylsulfonyl)-1,4,2,6-oxaazadisilinane
1,3-Bis(chloromethyl)-1,1,3,3-tetramethyldisiloxane
3,3-dimethyl-1-(trifluoromethylsulfonyl)-1,3-azasilolidine

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