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trifluridine

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Origin: China

Cas No: 70-00-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Quick Details

    CAS No.:
    70-00-8
    Other Names:
    Trifluridine
    MF:
    C10H11F3N2O5
    EINECS No.:
    200-722-8
    Place of Origin:
    Shandong, China (Mainland)
    Type:
    Anesthetic Agents
    Grade Standard:
    Medicine Grade
    Usage:
    Animal Pharmaceuticals
    Brand Name:
    FOUSI
    Model Number:
    FX70-00-8
    Purity:
    min99%
    Product name:
    Trifluridine
    CAS:
    70-00-8
    Description:
    white powder
    Synonyms:
    rifluorothyMidine
    Package:
    25kg/carton drum
    Assay:
    99%min
    useage:
    intermediates
    EINECS:
    200-722-8

    Packaging&Delivery

    Packaging Details
    Packaging & Delivery
    Packaging Details
    5kg/drum, 10kg/drum,25kg/drum,200kg/drum
    Port
    shanghai, tianjin,qingdao
    Port
    QINGDAO ,SHANGHAI
    Lead Time:
    Quantity(Kilograms)1 - 1>1
    Est. Time(days)3To be negotiated

  • Property

    CAS No.: 70-00-8 Formula: C10H11F3N2O5 Molecular Weight: 296.20000

    Basic Info

    Chemical Name trifluridine
    Synonyms

    Trifluorothymidine;
    Trifluridine;

    CAS No. 70-00-8
    Molecular Formula C10H11F3N2O5
    Molecular Weight 296.20000
    PSA 104.55000
    LogP -0.80390

    Properties

    Appearance & Physical State white crystalline powder
    Density 1.646g/cm3
    Melting Point 190-193ºC
    Refractive Index 1.534
    Storage Condition -20ºC

    Safety Info

    RTECS XP2087500
    Safety Statements S22-S36
    WGK Germany 3
    Risk Statements R20/21/22; R40
    Hazard Codes Xi

    Synthesis Route

    Trifluorothymine+thymidine→trifluridine+thymine
    2'-deoxyuridine+Trifluorothymine→trifluridine+Uracil
    Trifluoromethyl iodide+2'-deoxyuridine→trifluridine

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Intravenous LD50 - Lethal dose, 50 percent kill Rodent - rat 2946 mg/kg 1.Liver-other changes
    Intraperitoneal LD50 - Lethal dose, 50 percent kill Rodent - mouse 1931 mg/kg 1.Details of toxic effects not reported other than lethal dose value
    Intravenous LD50 - Lethal dose, 50 percent kill Rodent - mouse 3381 mg/kg 1.Nutritional and Gross Metabolic-weight loss or decreased weight gain

    Precursor

    [3-acetyloxy-5-[2,4-dioxo-5-(trifluoromethyl)pyrimidin-1-yl]oxolan-2-yl]methyl acetate
    2'-deoxyuridine
    1-Trifluoromethyl-1,2-Benziodoxol-3(1H)-One
    Trifluorothymine

    Downstream Product

    5-(2,4-dioxo-5-(trifluoromethyl)-3,4-dihydropyrimidin-1(2H)-yl)-2-(((4-methylbenzoyl)oxy)methyl)tetrahydrofuran-3-yl 4-methylbenzoate
    5-carboxy-2'-deoxyuridine

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