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URIDINE, 2'-BROMO-2'-DEOXY-5-METHYL-, 5'-BENZOATE 3'-METHANESULFONATE

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Origin: China

Cas No: 165047-01-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 165047-01-8 Formula: C18H19BrN2O8S Molecular Weight: 503.32100

Basic Info

Chemical Name	URIDINE, 2'-BROMO-2'-DEOXY-5-METHYL-, 5'-BENZOATE 3'-METHANESULFONATE
Synonyms	5-BENZOYL-3ETHANESULFONYL-2ROMOTHYMIDINE; 5'-BENZOYL-3-ETHANESULFONYL-2-BROMOTHYMIDINE; 5-BENZOYL-3-Methanesulfonyl-2-Bromothymidine;
CAS No.	165047-01-8
Molecular Formula	C18H19BrN2O8S
Molecular Weight	503.32100
PSA	142.14000
LogP	1.78850

Synthesis Route

2,2'-Anhydro-1-(5'-O-Benzoyl-3'-O-methylsulfonyl-β-D-arabinofuranosyl)thymine→URIDINE, 2'-BROMO-2'-DEOXY-5-METHYL-, 5'-BENZOATE 3'-METHANESULFONATE
ribothymidine→URIDINE, 2'-BROMO-2'-DEOXY-5-METHYL-, 5'-BENZOATE 3'-METHANESULFONATE
Sodium benzoate→URIDINE, 2'-BROMO-2'-DEOXY-5-METHYL-, 5'-BENZOATE 3'-METHANESULFONATE

Precursor

(2R,3R,4R,5R)-2-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-5-(((methylsulfonyl)oxy)methyl)tetrahydrofuran-3,4-diyl dimethanesulfonate
2,2'-Anhydro-1-(5'-O-Benzoyl-3'-O-methylsulfonyl-β-D-arabinofuranosyl)thymine
Sodium benzoate
ribothymidine

Downstream Product

zidovudine
stavudine
[(2S,5R)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)-2,5-dihydrofuran-2-yl]methyl benzoate
[3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl benzoate

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