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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Active Pharmaceutical Ingredients (APIs)> Genitourinary system> 1-[2-[4-[(E)-1-(4-iodophenyl)-2-phenylbut-1-enyl]phenoxy]ethyl]pyrrolidine
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1-[2-[4-[(E)-1-(4-iodophenyl)-2-phenylbut-1-enyl]phenoxy]ethyl]pyrrolidine

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Origin: China

Cas No: 116057-75-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 116057-75-1 Formula: C28H30INO Molecular Weight: 523.44800

    Description

    Idoxifene is a non-steroidal estrogen antagonist. It is structurally analogous to tamoxifen.

    Basic Info

    Chemical Name 1-[2-[4-[(E)-1-(4-iodophenyl)-2-phenylbut-1-enyl]phenoxy]ethyl]pyrrolidine
    Synonyms

    Idoxifene;
    pyrrolidino-4-iodotamoxifen;
    (E)-1-<4-<2-(N-pyrrolidino)ethoxy>phenyl>-1-(4-iodophenyl)-2-phenyl-1-butene;
    1-(2-{4-[(E)-1-(4-iodophenyl)-2-phenyl-but-1-enyl]phenoxy}ethyl)pyrrolidine;
    (E)-1-(2-(4-(1-(4-Iodophenyl)-2-phenyl-1-butenyl)phenoxy)ethyl)pyrrolidine;
    Iodoxifene;
    trans-1-(4-iodophenyl)-2-phenyl-1-(4-<2-(1-pyrrolidinyl)ethoxy>phenyl)-1-butene;
    (E)-1-(2-(4-(1-(4-Iodophenyl)-2-phenylbut-1-en-1-yl)phenoxy)ethyl)pyrrolidine;

    CAS No. 116057-75-1
    Molecular Formula C28H30INO
    Molecular Weight 523.44800
    PSA 12.47000
    LogP 7.07280

    Properties

    Density 1.329g/cm3
    Boiling Point 573.4ºC at 760mmHg
    Flash Point 300.6ºC
    Refractive Index 1.622
    Vapor Pressure 3.72E-13mmHg at 25°C

    Safety Info

    HS Code 2933990090

    Synthesis Route

    pyrrolidine+(E)-1-[4-(2-chloroethoxy)phenyl]-1-(4-iodophenyl)-2-phenyl-1-butene→1-[2-[4-[(E)-1-(4-iodophenyl)-2-phenylbut-1-enyl]phenoxy]ethyl]pyrrolidine
    pyrrolidine+1,4-Diiodobenzene→1-[2-[4-[(E)-1-(4-iodophenyl)-2-phenylbut-1-enyl]phenoxy]ethyl]pyrrolidine
    pyrrolidine+1-[4-(2-chloroethoxy)phenyl]-1-(4-iodophenyl)methanone→1-[2-[4-[(E)-1-(4-iodophenyl)-2-phenylbut-1-enyl]phenoxy]ethyl]pyrrolidine

    Precursor

    pyrrolidine
    1,4-Diiodobenzene
    1-[4-(2-chloroethoxy)phenyl]-1-(4-iodophenyl)methanone
    1-[4-(2-chloroethoxy)phenyl]-2-phenylbutan-1-one

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