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1,3-oxazole

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Origin: China

Cas No: 288-42-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 288-42-6 Formula: C3H3NO Molecular Weight: 69.06200

Description

Oxazole is the parent compound for a vast class of heterocyclic aromatic organic compounds. These are azoles with an oxygen and a nitrogen separated by one carbon. Oxazoles are aromatic compounds but less so than the thiazoles. Oxazole is a weak base; its conjugate acid has a pKa of 0.8, compared to 7 for imidazole.

Basic Info

Chemical Name	1,3-oxazole
Synonyms	(2,3-d) oxazole; Oxazole; 3-Azafuran; 3-oxazolane;
CAS No.	288-42-6
Molecular Formula	C3H3NO
Molecular Weight	69.06200
PSA	26.03000
LogP	0.67460

Properties

Appearance & Physical State	clear to pale yellow liquid
Density	1.05
Boiling Point	69-70ºC
Melting Point	-3ºC
Flash Point	19ºC
Refractive Index	1.425
Storage Condition	Refrigerator
Vapor Pressure	145.395mmHg at 25°C

Safety Info

Hazard Class	3
Safety Statements	S16-S26-S36
HS Code	2934999090
WGK Germany	3
Packing Group	II
RIDADR	UN 1993
Risk Statements	R11; R41
Hazard Codes	F; Xi
Signal Word	Danger
Symbol	GHS02, GHS05
Hazard Declaration	H225; H318
Caution Statement	P210; P280; P305 + P351 + P338

Synthesis Route

N-(3-BROMOPROPYL)PHTHALIMIDE+3H-Oxazole-2-thione→1,3-oxazole+N-(3-oxazol-2-ylsulfanyl-propyl)-phthalimide
1,3-oxazole-4-carboxylic acid→1,3-oxazole
Oxazole-2-Carboxylic Acid→1,3-oxazole

Precursor

N-(3-BROMOPROPYL)PHTHALIMIDE
Oxazole-2-Carboxylic Acid
3H-Oxazole-2-thione
1,3-oxazole-4-carboxylic acid

Downstream Product

2,5-Diphenyloxazole
N-formylformamide
Oxazole-2-Carboxylic Acid
2,4,5-triphenyl-1,3-oxazole

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