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2,4-Difluorophenol

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Origin: China

Cas No: 367-27-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
367-27-1
Other Names:
2 4-Difluorophenol
MF:
C6H4F2O, C6H4F2O
EINECS No.:
206-688-0
Place of Origin:
Shandong China, Shandong China
Type:
Pharmaceutical Intermediates, Syntheses Material Intermediates
Purity:
99.0%min, 99.0%min
Brand Name:
Fousi, Fousi
Model Number:
FS367-27-1
Application:
intermediates
Appearance:
Clear Colorless Liquid, Clear Colorless Liquid
Product name:
2 4-Difluorophenol
Form:
Powder
CAS:
367-27-1
EINECS:
206-688-0
usage:
intermediates
Packaging&Delivery
Packaging Details
5kg/drum, 10kg/drum,25kg/drum,200kg/drum
Port
QINGDAO ,SHANGHAI
Lead Time:
Quantity(Kilograms) 1 - 1 >1
Est. Time(days) 7 To be negotiated

Property

CAS No.: 367-27-1 Formula: C6H4F2O Molecular Weight: 130.09200

Description

2,4-Difluorophenol, is an organic building block used for the synthesis of various pharmaceutical compounds, such as antivirulence agents. It is also used in the synthesis of new α-Phenoxyacetamide derivatives, acting as type III secretion system of Pseudomonas aeruginosa PAO1, a gram-negative bacteria.

Basic Info

Chemical Name	2,4-Difluorophenol
Synonyms	2,4-Difluor-phenol; 4-Difluorophenol; 2,4-difluorophenole; 2,4-difluoro-phenol; 2,4-difluorophenyl; 2.4-Difluor-1-hydroxy-benzol; Phenol,2,4-difluoro;
CAS No.	367-27-1
Molecular Formula	C6H4F2O
Molecular Weight	130.09200
PSA	20.23000
LogP	1.67040

Properties

Appearance & Physical State	clear, yellow liquid
Density	1.36
Boiling Point	52-53ºC (19 mmHg)
Melting Point	22ºC
Flash Point	56ºC
Refractive Index	1.484-1.486
Water Solubility	slightly soluble
Stability	Stable at room temperature in closed containers under normal storage and handling conditions.
Storage Condition	Flammables area

Safety Info

Hazard Class	3
Safety Statements	S16-S26-S36/37/39-S45
HS Code	2907199090
WGK Germany	3
Packing Group	III
RIDADR	UN 1992
Risk Statements	R11; R20/21/22; R34
Hazard Codes	C

Synthesis Route

phenol→4-Fluorophenol+2-Fluorophenol
1-(tert-butyldimethylsilyloxy)-2,4-difluorobenzene→2,4-Difluorophenol
2,4-Difluorophenylboronic acid→2,4-Difluorophenol

Precursor

2,4-Difluoroaniline
2',4'-Difluoroacetophenone
1-(tert-butyldimethylsilyloxy)-2,4-difluorobenzene
phenol

Downstream Product

2-(2-chloro-4,6-difluorophenoxy)acetic acid
2-(2,4-difluorophenoxy)acetic acid
1-(Benzyloxy)-2,4-difluorobenzene
2,4-Difluoroanisole

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