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[3-[(4-bromophenyl)methyl]-2-butyl-4-chloro-1,2-dihydroimidazol-5-yl]methanol

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Origin: China

Cas No: 151012-31-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 151012-31-6 Formula: C15H18BrClN2O Molecular Weight: 357.67300

Description

Intermediate in the preparation of Losartan derivatives.

Basic Info

Chemical Name	[3-[(4-bromophenyl)methyl]-2-butyl-4-chloro-1,2-dihydroimidazol-5-yl]methanol
Synonyms	2-n-butyl-1-p-bromobenzyl-4-chloro-1H-imidazole-5-yl-methanol; 2-n-Butyl-4-chloro-1-(4-bromobenzyl)-1H-imidazole-5-methanol; [3-(4-bromo-benzyl)-2-butyl-5-chloro-3H-imidazol-4-yl]-methanol; 3-(4-BROMOBENZYL)-2-BUTYL-4-CHLORO-1H-IMIDAZOL-5-YLMETHANOL; 1H-Imidazole-5-methanol,1-[(4-bromophenyl)methyl]-2-butyl-4-chloro; (1-(4-bromobenzyl)-2-butyl-5-chloro-2,3-dihydro-1H-imidazol-4-yl)methanol; 2-n-butyl-4-chloro-5-hydroxymethyl-1-p-bromobenzyl-1H-imidazole; [3-(4-bromo-1-benzyl)-2-butyl-5-chloro-3H-imidazol-4-yl]-methanol;
CAS No.	151012-31-6
Molecular Formula	C15H18BrClN2O
Molecular Weight	357.67300
PSA	38.05000
LogP	4.18220

Properties

Density	1.42
Boiling Point	491.953ºC at 760 mmHg
Flash Point	251.324ºC
Refractive Index	1.605
Vapor Pressure	0mmHg at 25°C

Safety Info

HS Code	2933290090

Synthesis Route

N-(4-Bromobenzyl)-2-butyl-4-chloro-1H-imidazole-5-carboxyaldehyde→[3-[(4-bromophenyl)methyl]-2-butyl-4-chloro-1,2-dihydroimidazol-5-yl]methanol
2-Butyl-4-chloro-5-formylimidazole+4-Bromobenzyl Bromide→[3-[(4-bromophenyl)methyl]-2-butyl-4-chloro-1,2-dihydroimidazol-5-yl]methanol

Precursor

N-(4-Bromobenzyl)-2-butyl-4-chloro-1H-imidazole-5-carboxyaldehyde
2-Butyl-4-chloro-5-formylimidazole
4-Bromobenzyl Bromide

Downstream Product

Losartan potassium
[2-butyl-5-chloro-3-[[4-[2-(2-trityltetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol

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