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4-Amino-3-fluorophenol

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Origin: China

Cas No: 399-95-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
399-95-1
Other Names:
3-FLUORO-4-AMINOPHENOL
MF:
C6H6FNO
EINECS No.:
402-230-0
Place of Origin:
Jiangsu, China
Type:
Pharmaceutical Intermediates, Syntheses Material Intermediates
Purity:
>99%
Brand Name:
KPRX
Model Number:
CAS 399-95-1
Application:
Organic synthesis, pharmaceutical intermediate
Appearance:
off-white crystalline solid
Product name:
Intermediate 3-Fluoro-4-aminophenol 399-95-1
Name:
4--Amino-3-fluorophenol
Apperance:
White Crystalline Solid
Use:
Regorafenib intermediate
Packaging&Delivery
Packaging Details
20kg/carton
Pallet can be avialable for bulk order.
Port
Shanghai any port of China
Lead Time:
Quantity(Kilograms) 1 - 1000 >1000
Est. Time(days) 15 To be negotiated

Property

CAS No.: 399-95-1 Formula: C6H6FNO Molecular Weight: 127.11600

Basic Info

Chemical Name	4-Amino-3-fluorophenol
Synonyms	2-Fluoro-4-hydroxyaniline; 4-AMINO-3-FLUOROPHENOL MIN.; Aminofluorophenol3; IFLAB-BB F2108-0045; 3-FLUORO-4-AMINOPHENOL; 4-amino-5-fluorophenol; 4-Amino-3-fluor-phenol; 4-amino-3-fluoro-phenol; 4-Amino-3-fluorophen; 2-FLUORO-4-YDROXYANILINE;
CAS No.	399-95-1
Molecular Formula	C6H6FNO
Molecular Weight	127.11600
PSA	46.25000
LogP	1.69470

Properties

Appearance & Physical State	Brown crystal
Density	1.347 g/cm3
Boiling Point	263.3ºC at 760 mmHg
Melting Point	135-137ºC
Flash Point	113.1ºC
Refractive Index	1.601

Safety Info

Hazard Class	9
Safety Statements	S45-S53-S61
HS Code	2922299090
Packing Group	III
RIDADR	UN 3077
Risk Statements	R22
Hazard Codes	T; Xi; N

Synthesis Route

O-(3-fluorophenyl)hydroxylamine→3-Fluorophenol+4-Amino-3-fluorophenol
3-Fluoro-4-nitrophenol→4-Amino-3-fluorophenol
2-Fluoro-4-hydroxyaniline, HCl→4-Amino-3-fluorophenol

Precursor

Iron
2-Fluoro-4-hydroxyaniline, HCl
O-(3-fluorophenyl)hydroxylamine
3-fluoro-4-phenylazo-phenol

Downstream Product

8-fluoro-6-hydroxy-3,4-dihydro-1H-quinolin-2-one
Regorafenib hydrochloride
4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline
4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide

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