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5-fluorouridine

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Origin: China

Cas No: 316-46-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 316-46-1 Formula: C9H11FN2O6 Molecular Weight: 262.19200

Description

5-Fluoro Uridine is an active metabolite of Doxifluridine.

Basic Info

Chemical Name	5-fluorouridine
Synonyms	FURD; 5-fluoro-uridine; FUR; 5-FLUOROIDINE; 5-fur; 5-Fluor-uridin; 5-Fluorouridine; 5-FUrd; 5-fluoro-uridin; 1-(β-D-Ribofuranosyl)-5-fluorouracil; FLUOROURIDINE; 5-FU;
CAS No.	316-46-1
Molecular Formula	C9H11FN2O6
Molecular Weight	262.19200
PSA	124.78000
LogP	-2.71280

Properties

Appearance & Physical State	White Powder
Density	1.77g/cm3
Melting Point	180-183ºC
Refractive Index	1.641
Water Solubility	soluble
Stability	Stable under normal temperatures and pressures.
Storage Condition	2-8ºC

Safety Info

RTECS	YU8050000
Safety Statements	S22-S26-S36/37
HS Code	2942000000
WGK Germany	3
Risk Statements	R40
Hazard Codes	Xn

Synthesis Route

5-fluorouracil+ribothymidine→5-fluorouridine+thymine
[3,4-diacetyloxy-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl acetate→5-fluorouridine
uridine→5-fluorouridine

Precursor

5-fluorouracil
cytidine
[3,4-diacetyloxy-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl acetate
uridine

Downstream Product

α-D-ribofuranosyl phosphate, free acid
5-fluorouracil
choline
5-fluorocytidine

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