Home > Alcohols> 5'-O-(DIMETHOXYTRITYL)-2'-O-METHYL-5-METHYLURIDINE

5'-O-(DIMETHOXYTRITYL)-2'-O-METHYL-5-METHYLURIDINE

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Origin: China

Cas No: 115173-73-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 115173-73-4 Formula: C32H34N2O8 Molecular Weight: 574.62100

Basic Info

Chemical Name	5'-O-(DIMETHOXYTRITYL)-2'-O-METHYL-5-METHYLURIDINE
Synonyms	2'-Deoxy-5-difluoromethyluridine; F2-Tdr; 5-Difluoromethyl-2'-deoxyuridine;
CAS No.	115173-73-4
Molecular Formula	C32H34N2O8
Molecular Weight	574.62100
PSA	121.24000
LogP	3.14420

Synthesis Route

4,4'-Dimethoxytrityl chloride+1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(methoxymethyl)pyrimidine-2,4-dione→5'-O-(DIMETHOXYTRITYL)-2'-O-METHYL-5-METHYLURIDINE
3',5'-BIS-O-(T-BUTYLDIMETHYLSILYL)THYMIDINE→5'-O-(DIMETHOXYTRITYL)-2'-O-METHYL-5-METHYLURIDINE
3',5'-bis-O-(tert-butyldimethylsilyl)-5-(bromomethyl)-2'-deoxyuridine→5'-O-(DIMETHOXYTRITYL)-2'-O-METHYL-5-METHYLURIDINE

Precursor

3',5'-BIS-O-(T-BUTYLDIMETHYLSILYL)THYMIDINE
3',5'-bis-O-(tert-butyldimethylsilyl)-5-(bromomethyl)-2'-deoxyuridine
thymidine
4,4'-Dimethoxytrityl chloride

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