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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Active Pharmaceutical Ingredients (APIs)> Muscles, bones, and joints> medronic acid
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medronic acid

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Origin: China

Cas No: 1984-15-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 1984-15-2 Formula: CH6O6P2 Molecular Weight: 176.00200

    Description

    Medronic acid (conjugate base, medronate) is the smallest bisphosphonate. Its complex with radioactive technetium, 99mTc medronic acid, is used in nuclear medicine to detect bone abnormalities, including metastases.

    Basic Info

    Chemical Name medronic acid
    Synonyms

    MDP,Medronic acid;
    phosphonomethylphosphonic acid;
    MDP,Medronic acid,Methylenediphosphonic acid;
    MDP~Medronicacid;
    Medronic Acid;
    Methylenediphosphonic acid;
    Methylenebiphosphonic Acid;
    methylene biphosphonate;
    Methanebisphosphonic Acid;
    Methanediphosphonic Acid;
    METHYLENEBISPHOSPHONIC ACID;
    Medronic;
    methylenediphosphonate;
    MDP;

    CAS No. 1984-15-2
    Molecular Formula CH6O6P2
    Molecular Weight 176.00200
    PSA 134.68000
    LogP -0.70070

    Properties

    Appearance & Physical State white powder.
    Density 2.111 g/cm3
    Boiling Point 583.2ºC at 760 mmHg
    Melting Point 197-199ºC(lit.)
    Flash Point 306.5ºC
    Refractive Index 1.55
    Storage Condition 2-8ºC
    Vapor Pressure 4.08E-15mmHg at 25°C

    Safety Info

    RTECS SZ9138000
    Hazard Class 8
    Safety Statements 26-36/37/39-45
    HS Code 2931900090
    WGK Germany -
    Packing Group III
    RIDADR UN 3261 8
    Risk Statements R34
    Hazard Codes C

    Synthesis Route

    Tetraethyl methylenediphosphonate→medronic acid
    tetrabenzyl methylenediphosphonate→medronic acid
    Tetraisopropyl methylenediphosphonate→medronic acid

    Precursor

    methylenebisphosphonic acid tetrakis(trimethylsilyl) ester
    Tetraisopropyl methylenediphosphonate
    Methandiphosphonsaeuretetrabutylester
    Tetraethyl methylenediphosphonate

    Downstream Product

    bis(dimethoxyphosphoryl)methane
    Tetraethyl methylenediphosphonate
    bis(dichlorophosphoryl)methane

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