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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Active Pharmaceutical Ingredients (APIs)> Muscles, bones, and joints> Pamidronic acid
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Pamidronic acid

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Origin: China

Cas No: 40391-99-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 40391-99-9 Formula: C3H11NO7P2 Molecular Weight: 235.06900

    Description

    A biphosphonate bone resorption inhibitor.

    Basic Info

    Chemical Name Pamidronic acid
    Synonyms

    Pamidronic Acid See P172500;
    Pamidronic Acid;

    CAS No. 40391-99-9
    Molecular Formula C3H11NO7P2
    Molecular Weight 235.06900
    PSA 180.93000
    LogP -0.96300

    Properties

    Appearance & Physical State white crystalline powder
    Density 1.998 g/cm3
    Boiling Point 658.7ºC at 760 mmHg
    Melting Point 226-228ºC
    Flash Point 352.2ºC
    Refractive Index 1.611

    Synthesis Route

    β-alanine→Pamidronic acid
    [3-(benzyloxycarbonylamino)-1-hydroxy-1-phosphonopropyl]phosphonic acid→Pamidronic acid
    [3-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-1-hydroxy-1-phosphonopropyl]phosphonic acid→Pamidronic acid

    Precursor

    [3-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-1-hydroxy-1-phosphonopropyl]phosphonic acid
    β-alanine
    [3-(benzyloxycarbonylamino)-1-hydroxy-1-phosphonopropyl]phosphonic acid

    Downstream Product

    Olpadronic Acid

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