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methyl 3-cyclopropyl-3-oxopropanoate

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Origin: China

Cas No: 32249-35-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 32249-35-7 Formula: C7H10O3 Molecular Weight: 142.15200

Description

A reagent used in the synthesis of Pitavastatin.

Basic Info

Chemical Name	methyl 3-cyclopropyl-3-oxopropanoate
Synonyms	Methyl 3-Cyclopropyl-3-Oxopropionate; 3-Cyclopropyl-3-oxopropionic acid methyl ester; methyl cyclopropanecarbonylacetate; 3-cyclopropyl-3-oxopropanoic acid methyl ester; Methyl 3-cyclopropyl-3-oxopropanoate; methyl-3-cyclopropyl-3-oxopropanoate;
CAS No.	32249-35-7
Molecular Formula	C7H10O3
Molecular Weight	142.15200
PSA	43.37000
LogP	0.52860

Properties

Appearance & Physical State	Clear colorless oil
Density	1.174
Boiling Point	193ºC
Flash Point	74ºC
Refractive Index	1.475

Safety Info

Safety Statements	S26
HS Code	2918300090
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

Methanol+Meldrum's acid→methyl 3-cyclopropyl-3-oxopropanoate
Meldrum's acid+Cyclopropanecarbonyl Chloride→methyl 3-cyclopropyl-3-oxopropanoate
Cyclopropyl methyl ketone+dimethyl carbonate→methyl 3-cyclopropyl-3-oxopropanoate

Precursor

dimethyl carbonate
Meldrum's acid
Cyclopropanecarbonyl Chloride
Cyclopropyl methyl ketone

Downstream Product

4-(4-Fluorophenyl)-2-cyclopropylquinoline-3-carboxylic Acid Methyl Ester
pitavastatin calcium
4-Chloro-6-cyclopropyl-2-pyrimidinamine
Tert-buthyl Pitavastatin

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