Home > Chiral Compounds> 3',5'-Di-O-acetyl-2'-deoxyuridine

3',5'-Di-O-acetyl-2'-deoxyuridine

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Origin: China

Cas No: 13030-62-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 13030-62-1 Formula: C11H12N2O9 Molecular Weight: 316.22100

Description

An antitumor carbocyclic nucleoside.

Basic Info

Chemical Name	3',5'-Di-O-acetyl-2'-deoxyuridine
Synonyms	[(2R,3S,5R)-3-acetyloxy-5-(2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl acetate;
CAS No.	13030-62-1
Molecular Formula	C11H12N2O9
Molecular Weight	316.22100
PSA	157.15000
LogP	-0.41810

Properties

Density	1.4g/cm3
Refractive Index	1.555

Synthesis Route

2'-deoxyuridine+Acetic anhydride→3',5'-Di-O-acetyl-2'-deoxyuridine
1-(3,5-di-O-acetyl-2-bromo-2-deoxy-β-D-ribofuranosyl)-uracil→3',5'-Di-O-acetyl-2'-deoxyuridine
[but-3-ynoxy(diphenyl)methyl]benzene+3',5'-DIACETYL-5-IODO-2'-DEOXYURIDINE→3-(3,5-Di-O-acetyl-2-deoxy-β-D-erythro-pentofuranosyl)-6-(2-hydroxyethyl)furano[2,3-d]pyrimidin-2-one+3',5'-Di-O-acetyl-5-(4-hydroxybutynyl)-2'-deoxyuridine

Precursor

1-(3,5-di-O-acetyl-2-bromo-2-deoxy-β-D-ribofuranosyl)-uracil
2'-deoxyuridine
Acetic anhydride
3',5'-DIACETYL-5-IODO-2'-DEOXYURIDINE

Downstream Product

4-(hydroxyamino)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
5-CHLORO-2'-DEOXYURIDINE
3',5'-DIACETYL-5-IODO-2'-DEOXYURIDINE
3',5'-DI-O-ACETYL-5-BROMO-2'-DEOXY-D-URIDINE

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