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5-ETHYL-2'-DEOXYURIDINE

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Origin: China

Cas No: 15176-29-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 15176-29-1 Formula: C11H16N2O5 Molecular Weight: 256.25500

Description

5-Ethyl-2’-deoxyuridine was found to be a modulator of both antitumor action and pharmacokinetics of 5-Fluorouracil, a potent antineoplastic agent in clinical use.

Basic Info

Chemical Name	5-ETHYL-2'-DEOXYURIDINE
Synonyms	5-Ethyl-2'-deoxyuridine; 5-Ethyl-durd; Etudr; aedurid; edu; 5-ethyldeoxyuridine; EUdR Edoxudine; 2'-deoxy-5-ethyluridine; edoxudin; EDOXUDINE;
CAS No.	15176-29-1
Molecular Formula	C11H16N2O5
Molecular Weight	256.25500
PSA	104.55000
LogP	-1.26030

Properties

Density	1.389 g/cm3
Refractive Index	1.569

Synthesis Route

5-Ethyluracil+thymidine→thymine+5-ETHYL-2'-DEOXYURIDINE
5-Ethynyl-2′-deoxyuridine, (EdU)→5-ETHYL-2'-DEOXYURIDINE
5-ethenyl-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione→5-ETHYL-2'-DEOXYURIDINE

Precursor

5-Ethynyl-2′-deoxyuridine, (EdU)
5-Ethyluracil
1-[2-deoxy-3,5-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl]-5-iodouracil
5-ethenyl-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

Downstream Product

1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-ethylpyrimidine-2,4-dione
5-ethyl-1-[(2R,4S,5R)-5-(hydroxymethyl)-4-iodooxolan-2-yl]pyrimidine-2,4-dione
5-ethyl-1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]pyrimidine-2,4-dione

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