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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Active Pharmaceutical Ingredients (APIs)> Blood and blood forming organs> Betrixaban
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Betrixaban

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Origin: China

Cas No: 330942-05-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 330942-05-7 Formula: C23H22ClN5O3 Molecular Weight: 451.90500

    Description

    A novel anticoagulant. An oral direct inhibitor of factor Xa (FXa) for use in the prevention of venous thromboembolism (VTE).

    Basic Info

    Chemical Name Betrixaban
    Synonyms

    N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide;
    UNII-74RWP7W0J9;
    QCR-99;
    Bevyxxa®;
    N-(5-chloropyridin-2-yl)-2-[[4-(N,N-dimethylcarbamimidoyl)benzoyl]amino]-5-methoxybenzamide;
    Betrixaban (USAN);

    CAS No. 330942-05-7
    Molecular Formula C23H22ClN5O3
    Molecular Weight 451.90500
    PSA 110.90000
    LogP 4.69190

    Properties

    Density 1.3g/cm3
    Refractive Index 1.628

    Synthesis Route

    N-(5-chloro-pyridin-2-yl)-2-(4-cyano-benzoyl-amino)-5-methoxy-benzamide hydrochloride+Dimethylamine→Betrixaban
    N-(5-chloro-pyridin-2-yl)-2-(4-cyano-benzoyl-amino)-5-methoxy-benzamide hydrochloride+lithium,dimethylazanide→Betrixaban
    N-(5-chloro(2-pyridyl)){2-[(4-cyanophenyl)carbonylamino]-5-methoxyphenyl}-carboxamide+Dimethylamine→Betrixaban

    Precursor

    N-(5-chloro(2-pyridyl)){2-[(4-cyanophenyl)carbonylamino]-5-methoxyphenyl}-carboxamide
    Dimethylamine
    lithium,dimethylazanide
    5-Methoxy-2-nitrobenzoic acid

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