Home > All categories> Biochemicals and Pharmaceutical Chemicals> Active Pharmaceutical Ingredients (APIs)> Blood and blood forming organs> N-[2-hydroxy-6-[(4-methoxybenzoyl)amino]phenyl]-4-(4-methyl-1,4-diazepan-1-yl)benzamide

N-[2-hydroxy-6-[(4-methoxybenzoyl)amino]phenyl]-4-(4-methyl-1,4-diazepan-1-yl)benzamide

Get Latest Price >

FOB Price contact us for price

Origin: China

Cas No: 365462-23-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

Vendor:

Payment Terms:

Inquiry now

* Send an Inquiry to us

Add to wishlist

* Name your price
* Start order doesn't mean buying now

Products Specification
Product Description

Property

CAS No.: 365462-23-3 Formula: C27H30N4O4 Molecular Weight: 474.55200

Description

Darexaban (YM150) is a direct inhibitor of factor Xa created by Astellas Pharma. It is an experimental drug that acts as an anticoagulant and antithrombotic to prevent venous thromboembolism after a major orthopaedic surgery, stroke in patients with atrial fibrillation and possibly ischemic events in acute coronary syndrome. It is used in form of the maleate. The development of darexaban was discontinued in September 2011.

Basic Info

Chemical Name	N-[2-hydroxy-6-[(4-methoxybenzoyl)amino]phenyl]-4-(4-methyl-1,4-diazepan-1-yl)benzamide
Synonyms	Darexaban; UNII-KF322K101S; Tanexaban;
CAS No.	365462-23-3
Molecular Formula	C27H30N4O4
Molecular Weight	474.55200
PSA	94.14000
LogP	4.19620

Synthesis Route

N-(2-hydroxy-6-nitrophenyl)-4-(4-methyl-1,4-diazepan-1-yl)benzamide→N-[2-hydroxy-6-[(4-methoxybenzoyl)amino]phenyl]-4-(4-methyl-1,4-diazepan-1-yl)benzamide
2-amino-3-nitrophenyl 4-(4-methyl-1,4-diazepan-1-yl)benzoate hydrochloride→N-[2-hydroxy-6-[(4-methoxybenzoyl)amino]phenyl]-4-(4-methyl-1,4-diazepan-1-yl)benzamide
2-Amino-3-nitrophenol→N-[2-hydroxy-6-[(4-methoxybenzoyl)amino]phenyl]-4-(4-methyl-1,4-diazepan-1-yl)benzamide

Precursor

2-Amino-3-nitrophenol
N-(2-amino-6-hydroxyphenyl)-4-(4-methyl-1,4-diazepan-1-yl)benzamide
4-Methoxybenzoyl chloride
2-amino-3-nitrophenyl 4-(4-methyl-1,4-diazepan-1-yl)benzoate hydrochloride

Hot tags: n-[2-hydroxy-6-[(4-methoxybenzoyl)amino]phenyl]-4-(4-methyl-1,4-diazepan-1-yl)benzamide, China, manufacturers, suppliers, factory, wholesale, low price, high quality