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5-O-[1-[3,3-diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

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Origin: China

Cas No: 100427-26-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 100427-26-7 Formula: C36H41N3O6 Molecular Weight: 611.72700

Basic Info

Chemical Name	5-O-[1-[3,3-diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Synonyms	Lercanil (TN); 3-O-[1-[3,3-diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 5-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate; lercarnidipine; REC 15-2375; methyl 1,1,N-trimethyl-N-(3,3-diphenylpropyl)-2-aminoethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-pyridine-3,5-dicarboxylate; 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester; UNII-V7XTJ4R0BH; masnidipine; 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinecarboxylic acid 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester; Lercanidipine [INN]; Lercanidipine;
CAS No.	100427-26-7
Molecular Formula	C36H41N3O6
Molecular Weight	611.72700
PSA	113.69000
LogP	7.33040

Properties

Appearance & Physical State	White to light yellow solid
Density	1.177 g/cm3
Boiling Point	712.5ºC at 760 mmHg
Melting Point	118-120ºC
Flash Point	384.7ºC
Refractive Index	1.579
Vapor Pressure	3.77E-20mmHg at 25°C

Safety Info

HS Code	2942000000

Synthesis Route

Lercanidipine Hydrochloride→5-O-[1-[3,3-diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
N-methyl-3,3-diphenylpropan-1-amine→5-O-[1-[3,3-diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid→5-O-[1-[3,3-diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Precursor

Lercanidipine Hydrochloride
N-methyl-3,3-diphenylpropan-1-amine
5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid
2,N-Dimethyl-N-(3,3-Diphenylpropyl)-1-Amino-2-Propanol

Downstream Product

Lercanidipine Hydrochloride

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